Thermo Fisher Scientific HMOX1 Monoclonal Antibody (GTS-1)

Applications

Tested Dilution

Publications

Western Blot (WB)

5-10 µg/mL

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Immunohistochemistry (Paraffin) (IHC (P))

5-10 µg/mL

-

Immunohistochemistry (Frozen) (IHC (F))

5-10 µg/mL

-

Product Specifications

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

GTS-1

Immunogen

Rat heme oxygenase 1.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2118825

Product Specific Information

MA1-25475 will not react with rabbit.

Target Information

Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.