Thermo Fisher Scientific HMOX1 Monoclonal Antibody (GTS-1)
HMOX1 단백질을 검출하기 위한 마우스 단클론 항체로, Western blot 및 면역조직화학(IHC)에 적합합니다. 인간 시료에 반응하며, 농도 2 mg/mL의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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- MA125475
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 5–10 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 5–10 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC-F) | 5–10 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GTS-1 |
| Immunogen | Rat heme oxygenase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2118825 |
Product Specific Information
MA1-25475 will not react with rabbit.
Target Information
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules biliverdin and carbon monoxide.
HO consists of two homologous isozymes: inducible HO-1 and constitutively expressed HO-2.
HO-1 is induced by various stimuli including oxidative stress, inflammatory agents, transforming growth factor beta, and heat shock.
Increased expression of HO-1 is considered a cellular defense mechanism against oxidative stress, as elevated HO can generate more bilirubin, an antioxidant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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