
Thermo Fisher Scientific Phospho-DAB1 (Tyr220) Polyclonal Antibody
Phospho-DAB1 (Tyr220) 폴리클로날 항체로 인간, 생쥐, 랫트 시료에 반응. Western blot 및 IHC(파라핀) 적용 가능. 인산화된 Tyr220 위치에서 내인성 Dab1 검출. 고순도 정제 및 안정적 PBS/glycerol 저장 용액 형태.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DAB1 (Accession O75553), corresponding to amino acid residues around phosphorylated Tyr220 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816061 |
Product Specific Information
Antibody detects endogenous levels of Dab1 only when phosphorylated at Tyr220.
Target Information
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-104586_DAB1_O75553-1_Rabbit.svg, PA5-104586_DAB1_O75553-1_Rabbit_PDP.jpeg)
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