Thermo Fisher Scientific MASTL Polyclonal Antibody
Human MASTL 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 세포주기 조절 연구 및 암 관련 단백질 분석에 유용합니다.
- 카탈로그번호
- PA550180
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MASTL Polyclonal Antibody
Applications
Tested Application
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from C-terminal of human MASTL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635633 |
Product Specific Information
This antibody detects endogenous levels of total MASTL protein.
Target Information
MASTL (microtubule associated serine/threonine kinase-like) belongs to the MAST family within the AGC Ser/Thr protein kinase group.
It promotes mitotic progression and cell cycle reentry after DNA damage. Loss of MASTL leads to defects in chromosome condensation and separation, mediated primarily by inhibition of PP2A/B55 delta.
Overexpression of MASTL is associated with cancer progression, poor patient survival, and tumor recurrence in various cancers.
Mutations at this locus are linked to autosomal dominant thrombocytopenia (thrombocytopenia-2). Alternatively spliced transcript variants have been reported.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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