Thermo Fisher Scientific MRCK alpha Polyclonal Antibody
Human MRCK alpha 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 세포 골격 조절 관련 연구에 유용. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human MRCKα |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635634 |
Product Specific Information
This antibody detects endogenous levels of total MRCK alpha protein.
Target Information
CDC42BPA (MRCKA) is a serine/threonine kinase involved in actin cytoskeleton assembly and organization. Three independent coiled-coil domains and the N-terminal region preceding the kinase domain mediate intermolecular interactions leading to MRCK alpha multimerization. Transautophosphorylation is essential for regulating MRCK alpha catalytic activity. Binding of phorbol esters releases autoinhibition, enabling N-terminal dimerization and kinase activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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