Thermo Fisher Scientific TRPA1 (extracellular) Polyclonal Antibody
TRPA1 단백질의 외세포 루프를 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성. WB, IHC, ICC/IF, Flow, IP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 동결건조 형태. 냉동(-20°C) 보관 권장.
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- ACC-037-xxxxx (3개 옵션)
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Thermo Fisher Scientific TRPA1 (extracellular) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (IHC) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 5 µg |
| Immunoprecipitation (IP) | 6.5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)NSTGIINETSDHSE, corresponding to amino acid residues 747–760 of human TRPA1, 1st extracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
- Ships as lyophilized powder at room temperature; store at -20°C upon arrival.
- Reconstituted solution stable at 4°C for up to 1 week; for long-term storage, aliquot and keep at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
TRPA1 is a TRP-related ion channel responsive to cold temperatures and pungent compounds, involved in nociceptor and hair cell transduction. It is expressed mainly in sensory neurons and lung epithelia and may serve as a therapeutic target for cold hyperalgesia due to inflammation or nerve injury. TRPA1 expression is also associated with oncogenic transformation and is structurally related to ankyrin and transmembrane proteins. Though its precise function remains unclear, studies suggest roles in signal transduction and growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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