Thermo Fisher Scientific TNFRSF4 Monoclonal Antibody (UMAB276), UltraMAB
인간 TNFRSF4(OX40/CD134)를 인식하는 Mouse IgG1 단클론 항체. IHC, ChIP, Peptide Array 등 다양한 응용에 적합. 동결건조 형태로 제공되며, 재구성 시 1 mg/mL 농도 권장. T세포 활성화 및 면역반응 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:300 |
| ChIP assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB276 |
| Immunogen | Full length human recombinant protein of human TNFRSF4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
OX40 (also known as CD134) is a protein receptor expressed on the surface of T cells, which play a key role in immune response. Upon activation, OX40 enhances T-cell proliferation and survival, resulting in a stronger immune reaction against cancer cells and pathogens.
OX40 agonists have demonstrated potential in immunotherapy applications, improving outcomes of chemotherapy and checkpoint inhibitor treatments, and showing promise in autoimmune and allergy research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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