Thermo Fisher Scientific CD13 Monoclonal Antibody (UMAB275), UltraMAB
인간 CD13 단백질을 인식하는 UMAB275 단클론 항체로 IHC(P)에서 검증됨. 비결합형 액상 항체이며 친화 크로마토그래피로 정제됨. PBS, BSA, 글리세롤 완충액에 보관되며 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB275 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 668–967 of human CD13 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. It acts as a metalloprotease that catalyzes the removal of neutral amino acids from small peptides, influencing activation or inactivation of bioactive peptides. CD13 is involved in extracellular matrix degradation, antigen processing, and signal transduction. It plays roles in inflammatory responses, intercellular contact regulation, cell motility, and vascularization. CD13 expression is observed in granulocytes, monocytes, and myeloid leukemia cells, and is associated with protection against apoptosis and poor carcinoma prognosis. Additionally, CD13 functions as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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