Thermo Fisher Scientific Vimentin (Mesenchymal Cell Marker) Monoclonal Antibody (VM452)
Mesenchymal cell marker Vimentin 단백질을 인식하는 Mouse monoclonal antibody(VM452). 다양한 종에 반응하며 WB, IHC, Flow 등에서 사용 가능. Protein A/G 정제, PBS buffer, 4°C 보관. Mouse 및 Rat에는 반응하지 않음.
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Thermo Fisher Scientific Vimentin (Mesenchymal Cell Marker) Monoclonal Antibody (VM452)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Chicken, Cat, Goat, Human, Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VM452 |
| Immunogen | Recombinant full-length human vimentin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
- CF 488 conjugate available
- Custom conjugation requests accepted
Product Specific Information
Does not react with Mouse or Rat.
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular protein transport between the nucleus and plasma membrane. Vimentin is co-expressed with desmin during early development and later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by facilitating cholesterol transport within mitochondria through cytoskeletal changes induced by phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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