Thermo Fisher Scientific STAT6 Recombinant Rabbit Monoclonal Antibody (SY13-09)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:3000

-

Immunocytochemistry (ICC/IF)

1:200-1:500

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

SY13-09

Immunogen

Synthetic peptide within human stat6 c terminal if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:STAT6,uniProtId:P42226-1,ncbiNodeId:9606,antigenRange:847,antigenLength:847,antigenImageFileName:MA5-42422_STAT6_P42226-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42422_STAT6_P42226-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2911563

Product Specific Information

Positive Control: NIH/3T3 cell lysate, Hela cell lysate, Raji cell lysate, Daudi cell lysate, Hela, HepG2, NIH/3T3, mouse lung tissue, human kidney tissue.

Subcellular Location: Cytoplasm, Nucleus.

Target Information

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.