Thermo Fisher Scientific MUC16/CA125 Monoclonal Antibody (OCA125, 1900)
인간 MUC16/CA125 항원을 인식하는 마우스 단클론 항체로, 포르말린 고정 파라핀 절편 IHC에 적합. 단백질 A/G로 정제된 액상 형태이며, PBS(pH 7.4)에 보존제 없이 제공. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OCA125, 1900 |
| Immunogen | Full-length native MUC16 protein purified from human ovarian carcinoma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
CA125 determinant is present on a high molecular weight mucin-like glycoprotein. It is found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium, and peritoneum.
In adult tissues, CA125 is expressed in epithelial cells of fallopian tube, endometrium, endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland. It is also found in mesothelial cell linings and in ovarian tumors of serous, endometrioid, or clear cell types, as well as adenocarcinomas of mullerian type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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