Thermo Fisher Scientific BNP Polyclonal Antibody
BNP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관됩니다. 심혈관 연구 및 BNP 관련 단백질 분석용으로 권장됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–134 of BNP (Uniprot ID: P16860) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155368 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
This gene belongs to the natriuretic peptide family and encodes a secreted cardiac hormone. The protein undergoes two cleavage events—one intracellularly and another after secretion into the blood. Its biological actions include:
- Natriuresis and diuresis
- Vasorelaxation
- Inhibition of renin and aldosterone secretion
- Regulation of cardiovascular homeostasis
Elevated levels of this protein in the bloodstream are indicative of heart failure. Mutations have been linked to postmenopausal osteoporosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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