Thermo Fisher Scientific DHDH Monoclonal Antibody (T101)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250 - 1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

T101

Immunogen

Recombinant type 2 dihydrodiol dehydrogenase from human lung cancer

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2061186

Product Specific Information

This antibody recognizes the DD1 or DD2 isoforms.

In Western blot, this antibody detects a ~32 kDa band in human breast cancer tissue and porcine liver tissue.

Target Information

This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.