Thermo Fisher Scientific Phospho-CEBP alpha (Thr226) Polyclonal Antibody
CEBP alpha의 Thr226 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:50–1:200 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human CEBP alpha around the phosphorylation site of Thr226 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The C/EBP (CCAAT/enhancer binding protein) family of transcription factors—alpha, beta, delta, and epsilon—are widely expressed proteins found in various tissues. These proteins contain an evolutionarily conserved five-amino acid regulatory domain motif (RDM) that conforms to the consensus sequence (I/V/L)KXEP.
C/EBP transcription factors play major roles in metabolic regulation in liver and adipose tissues and act in cascades promoting adipocyte differentiation.
Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation sites and have distinct roles in gene regulation.
In the nervous system, C/EBPs are involved in nerve growth factor signaling, synaptic plasticity modulation, and inflammatory response regulation in Alzheimer’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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