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Thermo Fisher Scientific IL17RD Polyclonal Antibody
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IL17RD 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, Flow Cytometry에 사용 가능. 인간 시료 반응성. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 연구용 전용 제품.
- 카탈로그번호
- PA547287
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 05. 오전 11:09
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific PA547287 IL17RD Polyclonal Antibody 100 ug pk판매 단위 pk ·
재고 확인 필요
921,800원VAT 포함 1,013,980원
Thermo Fisher Scientific · Thermo Fisher Scientific IL17RD Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human IL-17RD/SEF (Ala27–Arg299) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606536 |
Product Specific Information
- In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse (rm) IL-17RD is observed.
- Less than 10% cross-reactivity with recombinant human (rh) IL-17RC, rmIL-17B R, and rhIL-17R is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
IL17RD acts as a feedback inhibitor of fibroblast growth factor (FGF)-mediated Ras-MAPK signaling and ERK activation.
It may inhibit FGF-induced FGFR1 tyrosine phosphorylation and regulate nuclear ERK signaling by preventing nuclear translocation of activated ERK without affecting cytoplasmic phosphorylation.
It also mediates JNK activation and may play a role in apoptosis and early fate specification of GnRH-secreting neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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