Thermo Fisher Scientific Heparin Cofactor II Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1 µg/mL

-

Immunoprecipitation (IP)

25 µg/mL

-

Neutralization (Neu)

1.23 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Serpin D1/Heparin Cofactor II Glu24-Ser478 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Heparin Cofactor II,uniProtId:P49182-1,ncbiNodeId:10090,antigenRange:24-478,antigenLength:478,antigenImageFileName:PA5-47108_Heparin_Cofactor_II_P49182-1_Goat.svg,antigenImageFileNamePDP:PA5-47108_Heparin_Cofactor_II_P49182-1_Goat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608673

Product Specific Information

In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Serpin A1, rhSerpin A3, rhSerpin A5, recombinant mouse (rm) Serpin C1, and rmSerpin F2 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.