OsmoTECH® PRO Multi-Sample Micro-Osmometer

Automation to fit your growing lab

• Just a 30 μL sample volume is needed, facilitating sample-limited applications
• Walk-away testing with 20-position turntable
• Data integrity features support 21 CFR part 11, GMP and EU Annex 11

Ease of Use, Accurate Osmolality Measurements, & Reliable Results

OsmoTECH PRO incorporates freezing point technology to test osmolality ensuring accurate and precise measurement of your essential parameter in process control and QC. It is enhanced with advanced data management options and can integrate seamlessly into high throughput workflows.

Highlighted features

• Multi-sample Osmometer
• Walk-away Testing
• Reliable & Consistent Performance
• Robust Data Integrity
• Intuitive Interface
• Pharmacopeia Compliance

Integrates Easily in Your Bioprocessing Workflow

Optimize your workflow with automated testing and cleaning while maintaining regulatory compliance (including 21 CFR part 11), and data management needs of busy bioprocessing and biomanufacturing labs.

The OsmoTECH PRO Multi-Sample Micro-Osmometer ensures your lab is more efficient, freeing you up to spend more time on what matters.

Industry Applications

In Biotech Labs

Maximize biologic yield, quality, and purity by optimizing and ensuring the quality and consistency of your buffers, media, product, excipients, and process parameters.

In Food & Beverage Labs

Boost efficiency, ensure product quality, and maintain process consistency with osmolality testing from formulation to release.

Product Features

Effortlessly run multiple samples

• 20- position sample turntable
• Walk-away testing
• Intuitive touch-screen interface for easy operation

Small sample requirement

• Just a 30 μL sample volume

Industry leading accuracy and precision

• Freeze-point depression technology
• 0 – 2000 mOsm/kg H2O

Seamless process control and traceability

• Bi-directional capability with OPC-UA to lab management and middleware software​

Preserve your audit trail

• Integrated barcode scanner for sample identification and reduced transcription errors
• Automatic, manual, synchronous back up
• Complete time-stamped record of usage, role, and actions requiring reason for settings changes
• Ability to annotate test results via the handy comments field

Protect your data

• Active Directory/LDAP options minimize manual input and the risk of errors
• Automatic or manual backups
• 3 levels of user access
• Automatic logout timer
• Unlimited results and events storage

Support compliance

• 21 CFR part 11 / EU Annex 11
  • e-Signature
  • Three level user access
  • Password protection
  • And more
• GMP environment
• Pharmacopeia osmolality testing guidelines

Robust and flexible data management

• Network share (pdf & csv)
• Open Protocol Communication (OPC-UA)
• LIS (TCP/IP) Communication
• Bi-directional data management capability with OPC-UA to connect lab management (LIMS) and middleware software
• Active directory
• USB download
• Optional dot-matrix printer

Sample type	Aqueous-based solution
Sample volume	30 ± 1 μL
Test time	90 seconds (typical) to test single sample 40 minutes (typical) to test 20 samples
Sample Capacity	Multi sample
Resolution	1 mOsm/kg H2O
Range	0-2000 mOsm/kg H2O
Accuracy2	0-400 mOsm/kg H2O: mean value ± 3 mOsm/kg H2O from nominal value 400-2000 mOsm/kg H2O: mean value ± 0.75% from normal value
Within-run Repeatability2	0-400 mOsm/kg H2O: standard deviation ≤ 3 mOsm/kg H2O from nominal value 400-2000 mOsm/kg H2O: Coefficient of Variation ≤ 0.75%
Temperature effects3	Less than 1 mOsm/kg H2O per 5 °C (9 °F) ambient temperature change
Calibration	0*, 50, 850, and 2000* mOsm/kg H2O (* optional)
Supported Languages	Simple Chinese, English, French, German, Italian, Japanese, Korean, Russian, Spanish, Turkish
Storage temperature	-20 °C to +45 °C (-4 °F to +113 °F)
Electrical voltage	100 to 240 VAC (50/60 Hz)
Power consumption	60 Watts
Dimensions (D x W x H)	39 cm x 25 cm x 46 cm (15.3” x 10” x 18”)
Net weight	13.2 kg (29 lbs.)
Shipping weight	17.7 kg (39 lbs.)
Warranty	One-year limited warranty on workmanship and parts

Osmometer Calibration Standards and Reference Solutions

SK-TECHPRO	Convenience Kit (Includes: 3MA029, 3MA005, 3MA085, 3MA200, 3LA028, 222825, 222840, 202850, 240821)
3MA029	Clinitrol™ 290 Reference Solution, 10×2 mL ampules
3MA000	0 mOsm/kg H2O Calibration Standard, 10×2 mL ampules
3MA085	850 mOsm/kg H2O Calibration Standard, 10×2 mL ampules
3MA200	2000 mOsm/kg H2O Calibration Standard, 10×2 mL ampules
3LA028	Osmolality Linearity Set 100-2,000 mOsm 5x2x5 mL
3MA002	Osmolality Linearity Set, 100-2,000 mOsm 5x2x2 mL

Supplies

222825	Disposable sample tubes
222840	Probe wiper rings
202850	Swab Cleaner Kit
240821	Sampler Tips, 50/pkg

Accessories

135022	Epson Dot Matrix Printer (sold-separately)
AN2TP5	Dot Matrix Printer Paper

Clinitrol™ 290 Reference Solution

10 x 2 mL Ampules

View Product

Osmolality Linearity Set

0, 500, 900, 1500, 2000 mOsm/kg H2O 5x 2x 2 mL Ampules

View Product

Osmometer Calibration Standards

Available from 0-4000 mOsm/kg H2O 10 x 2 mL Ampules

View Product

Protinol™ Protein-Based Controls

Protinol 3-Level Osmometer Control 3x3x3 mL

View Product

###### All models support Pharmacopeia testing guidelines	New! OsmoTECH® HT Automated Micro-Osmometer	OsmoTECH® PRO Multi-Sample Micro-Osmometer	OsmoTECH® XT Single-Sample Micro-Osmometer	OsmoTECH® Single-Sample Micro-Osmometer	Model 3250 Single-Sample Osmometer Being discontinued Dec. 31, 2020
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Best for labs with daily sample processing needs of:	>20/day	>10/day	1-10/day	1-10/day	1-10/day
Sample volume	40 µL	30 µL	20 µL	20 µL	250 µL
Sample introduction	96 well plate	Sample cup	One-step direct	One-step direct	Sample cup
Operating range (mOsm/kg H2O)	0 - 2,000 mOsm/kg H2O	0 - 2,000 mOsm/kg H2O	0 – 4,000 mOsm/kg H2O	0 - 2,000 mOsm/kg H2O	0 - 4,000
Test time (seconds)	140	90	Less than 150 in low range, Less than 190 in high range	90	120
Multi-sample capacity
Automated cleaning between samples
Complex Matrices (High Concentrations, Sugars, & Proteins)
Integrated barcode scanner
Onboard Video Instructions
Multi-language touchscreen display
Supports 21 CFR Part 11 & EU Annex 11 compliance
Electronic Signature (Review & Approve)
Supports Pharmacopeia testing guidelines compliance
Username & Password Compatibility (With Active Directory)
Dot-matrix Printer
Network Connection
Network share
Automatic backup
Control device remotely via OPC-UA
USB
Webserver for remote data viewing
Data Storage Capacity	Unlimited	Unlimited	Unlimited	Unlimited
Levels of users access	3 Levels	3 Levels	3 Levels	3 Levels
Data Format	.csv & pdf	.csv & pdf	.csv & pdf	.csv & pdf
Part #	OSMOTECHHT	OsmoTECHPRO	OsmoTECHXT	OsmoTECH	3250
Download Chart as a PDF 1. Sold separately	Learn More Request Pricing	Learn More Request Pricing	Learn More Request Pricing	Learn More Request Pricing	Learn More Request Pricing