Thermo Fisher Scientific ARHGAP32 Polyclonal Antibody
Human ARHGAP32 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 세포 신호 조절 및 신경세포 분화 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human p190-A RhoGAP. Recombinant protein control fragment (Product #RP-102828) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645136 |
Product Specific Information
Immunogen sequence:
AVATTEDNLS SSYSAVALDK AYFQTDRPAE QFHLQNNAPG NCDHPLPETT ATGDPTHSNT TESGEQHHQV DLTGNQPHQA YLSGDPEKAR ITSVP
Highest antigen sequence identity to the following orthologs:
- Mouse: 65%
- Rat: 74%
Target Information
GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases.
May be involved in neuronal cell differentiation during neurite formation.
Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines.
May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation.
Isoform 2 exhibits higher GAP activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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