Thermo Fisher Scientific IL-13 Polyclonal Antibody
쥐 IL-13 단백질을 인식하는 Rabbit Polyclonal 항체로, ELISA에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다. 면역 및 염증 반응 연구용으로 적합하며, 재구성 시 500 µg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived rat IL-13 recombinant protein (Position: P22–H131) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746581 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells and is involved in regulating inflammatory and immune responses. It down-regulates macrophage activity, inhibiting the production of pro-inflammatory cytokines and chemokines. IL-13 also plays a role in allergen-induced asthma through mechanisms independent of IgE and eosinophils. Additionally, IL-13 regulates B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching in B cells. Structurally, IL-13 resembles IL-3, IL-4, IL-5, and GM-CSF. The IL-13 gene is located on chromosome 5q within a cytokine gene cluster near IL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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