Thermo Fisher Scientific Phospho-Rb (Ser807, Ser811) Polyclonal Antibody
Rb 단백질의 Ser807/Ser811 인산화 상태를 검출하는 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 인간 및 설치류 반응성. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues around pSer807/811 of human Rb |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 52 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977405 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine residues and forms complexes with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein regulates transcription, and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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