Thermo Fisher Scientific Phospho-TYK2 (Tyr1054, Tyr1055) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pTyr1054/1055 of human Tyk2 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TYK2,uniProtId:P29597-1,ncbiNodeId:9606,antigenRange:1055,antigenLength:1187,antigenImageFileName:PA5-17898_TYK2_P29597-1_Rabbit.svg,antigenImageFileNamePDP:PA5-17898_TYK2_P29597-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

121 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10983769

Product Specific Information

It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with Tyk2 protein phosphorylated at other sites.

Target Information

Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.