Thermo Fisher Scientific Phospho-TYK2 (Tyr1054, Tyr1055) Polyclonal Antibody
TYK2 단백질의 Tyr1054/1055 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, 인간 시료 반응성 확인됨. 항원 친화 크로마토그래피로 정제된 액상 형태로, 보존제가 포함되지 않음. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr1054/1055 of human Tyk2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 121 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10983769 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with Tyk2 protein phosphorylated at other sites.
Target Information
Tyrosine Kinase 2 (TYK2), a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. It may contribute to antiviral immunity.
A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES), a primary immunodeficiency characterized by elevated serum immunoglobulin E.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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