Thermo Fisher Scientific SLC22A5 Polyclonal Antibody
SLC22A5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, 인간, 생쥐, 랫드 반응성. 고순도(>95%) 항원 친화 크로마토그래피로 정제됨. 액상 형태, 1 mg/mL 농도, PBS/glycerol buffer로 안정화.
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Thermo Fisher Scientific SLC22A5 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length human SLC22A5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2554042 |
Product Specific Information
- Detects endogenous SLC22A5 protein at approximately 63 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Carnitine (β-hydroxy-γ-trimethylaminobutyrate) is a small, highly polar compound that facilitates β-oxidation of long-chain fatty acids.
Organic cation/carnitine transporters (OCTN) help eliminate cationic compounds and transport carnitine for kidney reabsorption.
OCTN proteins localize to epithelial cell plasma membranes and show distinct tissue expression patterns:
- OCTN1: kidney, trachea, bone marrow, fetal liver
- OCTN2: kidney, skeletal muscle, placenta, heart
- OCTN3: testis (strong), kidney (weak)
Mutations in OCTN2 cause systemic carnitine deficiency (SCD), an autosomal recessive disorder associated with cardiomyopathy, skeletal myopathy, lethargy, hypoglycemia, and hyperammonemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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