Thermo Fisher Scientific UBE2C Polyclonal Antibody
Human UBE2C 단백질을 인식하는 Goat Polyclonal 항체로 Western blot에 적합. 0.5 mg/mL 농도의 액상 항체이며 TBS(pH 7.3)와 0.5% BSA 포함. -20°C에서 보관, 동결/해동 반복 피할 것. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-SGDKGISAFPESDN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933140 |
Product Specific Information
- This antibody is expected to recognize isoforms 1 (NP_008950.1), 2 (NP_861515.1), and 4 (NP_861517.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
The UBE2C gene encodes a member of the E2 ubiquitin-conjugating enzyme family.
This protein is essential for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression.
It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
In vitro, it catalyzes Lys-11- and Lys-48-linked polyubiquitination.
UBE2C acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis by promoting degradation of APC/C substrates via the proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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