Thermo Fisher Scientific OCT1 (POU2F1) Recombinant Rabbit Monoclonal Antibody (13H18L58)
OCT1 (POU2F1) 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot, ICC/IF, ChIP 등 다양한 응용에 적합. 높은 특이성과 일관된 결과 제공. 인간 반응성, 단기 4°C 보관, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | 2 µg/million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 13H18L58 |
| Immunogen | Protein corresponding to human OCT-1 [aa1–aa200] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809221 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, and Cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates promoters of genes such as small nuclear RNAs (snRNA), histone H2B, and immunoglobulins.
It modulates transcription transactivation by NR3C1, AR, and PGR.
During human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1, enabling transcription of viral immediate early genes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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