Thermo Fisher Scientific hnRNP L Monoclonal Antibody (4D11)
Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합한 hnRNP L 단클론 항체. Human, Mouse 등 여러 종에 반응하며, 4D11 클론으로 제작됨. Protein A로 정제된 액상 항체로, 안정적인 보관 및 재현성 높은 결과 제공.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 0.25–0.5 µg/mL | |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | |
| ELISA | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Non-human primate, Bovine |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D11 |
| Immunogen | Human hnRNP proteins from HeLa cells, purified by affinity chromatography on ssDNA agarose |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2248549 |
Product Specific Information
- Recommended positive control: MDBK
- A band of approximately 65 kDa can be detected.
Target Information
Heterogeneous nuclear RNAs (hnRNAs), including mRNA precursors and mature mRNAs, are associated with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes. hnRNP L is among the proteins stably associated with these complexes and plays a key role in mRNA formation, packaging, processing, and function.
It is primarily located in the nucleoplasm but can also be found outside of it. hnRNP proteins shuttle between the nucleus and cytoplasm, suggesting potential cytoplasmic functions. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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