
Thermo Fisher Scientific SIAH1 Recombinant Rabbit Monoclonal Antibody (PSH0-46)
SIAH1 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. 인간, 생쥐, 랫트 반응성. Expi293 발현, Protein A 정제, 비결합형 액상 형태. 세포 내 SIAH1 단백질 검출 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PSH0-46 |
| Immunogen | Synthetic peptide within human SIAH1 aa 1–50 / 282 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3075018 |
Product Specific Information
- Sequence Similarities: 100% Mouse/Rat
- Tissue Specificity: Widely expressed at a low level. Down-regulated in advanced hepatocellular carcinomas.
- Positive Control: Jurkat, HeLa, HepG2, A549 cell lysates; human, mouse, and rat brain/testis tissues.
- Subcellular Location: Cytoplasm, Nucleus
- Predicted Band Size: 31.1 kDa
Target Information
This gene encodes a protein that is a member of the seven in absentia homolog family. The protein functions as an E3 ubiquitin ligase involved in ubiquitination and proteasome-mediated degradation of specific proteins. Its activity is implicated in Parkinson’s disease, regulation of hypoxia response, and induction of apoptosis. Alternative splicing yields multiple transcript variants, some encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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