Thermo Fisher Scientific DDX39B Monoclonal Antibody (OTI2C5), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing.
The encoded protein is an essential splicing factor required for U2 small nuclear ribonucleoprotein association with pre-mRNA and also plays a key role in mRNA export from the nucleus to the cytoplasm.
A cluster of genes (BAT1–BAT5) is localized near TNF alpha and TNF beta genes within the human MHC class III region.
Mutations in this gene may be associated with rheumatoid arthritis.
Alternatively spliced transcript variants encoding the same protein have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.