Thermo Fisher Scientific Complement C5a Monoclonal Antibody (D2)
Human C5a 단백질을 인식하는 Mouse monoclonal antibody (Clone D2). Western blot에 사용 가능하며, 1 mg/mL 농도의 액상 형태로 제공. Protein A/G로 정제되어 있으며 PBS + 50% glycerol에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 0.01–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D2 |
| Immunogen | Recombinant C5a (Thr678–Arg751) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2912807 |
Target Information
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is composed of alpha and beta polypeptide chains linked by a disulfide bridge. An activation peptide, C5a, is an anaphylatoxin possessing potent spasmogenic and chemotactic activity, derived from the alpha chain via cleavage with a convertase. The C5b macromolecular cleavage product forms a complex with the C6 complement component, serving as the basis for the membrane attack complex formation. Mutations in this gene cause complement component 5 deficiency, leading to severe recurrent infections, and have been linked to susceptibility to liver fibrosis and rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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