Thermo Fisher Scientific CD42b Monoclonal Antibody (AK2)
CD42b 단백질을 인식하는 마우스 모노클로날 항체로, 인간 혈소판 및 거핵세포에서 발현되는 GPIbα를 타깃함. WB, ICC/IF, Flow Cytometry 등 다양한 실험에 사용 가능. 비결합형 항체이며 1 mg/mL 농도로 제공. 연구용으로만 사용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1–4 µg/mL |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AK2 |
| Immunogen | Human platelets |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912929 |
Available Conjugated Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD42b (GPIb alpha), a 135–145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) form a disulfide-linked heterodimer (CD42b/c; 160 kDa), which associates noncovalently with CD42a and CD42d.
Target Information
CD42b is a platelet activation marker involved in coagulation as an aggregating factor. It interacts with extracellular matrix and adhesion molecules. CD42b expression and activation are regulated by VEGF and PDGF. Together with GPIb beta, GPIX, and GPV, CD42b forms the GPIb-IX-V receptor complex essential for platelet-rich thrombus formation. It binds von Willebrand factor (VWF), thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1, and P-selectin. The extracellular domain contributes to metastasis. CD42b is expressed on platelets and megakaryocytes in bone marrow. Mutations in CD42b are associated with Bernard-Soulier syndrome and platelet-type von Willebrand disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항원 구조 및 관련 이미지가 포함됨)
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Complement C5a Monoclonal Antibody (D2)
646,200원
Thermo Fisher Scientific
Thermo Fisher Scientific DNAH11 Monoclonal Antibody (C5)
608,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CD42b Monoclonal Antibody (AK2)
669,600원
Thermo Fisher Scientific
Thermo Fisher Scientific GIP Monoclonal Antibody (C2)
761,500원
Thermo Fisher Scientific
Thermo Fisher Scientific GREM1 Monoclonal Antibody (C1)
358,800원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|