Thermo Fisher Scientific Mu-Calpain Monoclonal Antibody (15C10)
Mu-Calpain 단일클론 항체(15C10)는 인간, 소, 생쥐, 랫드에 반응하며 Western blot, ELISA, IP 등 다양한 응용에 사용 가능. 단백질 A/G 정제, PBS+50% glycerol 저장, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 3 publications |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | View 1 publication |
| Flow Cytometry (Flow) | - | View 1 publication |
| ELISA | 0.5–1.0 µg/mL | View publications |
| Immunoprecipitation (IP) | 1.0–2.0 µg/mL | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 15C10 |
| Immunogen | Human Calpain protein purified from placenta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2069339 |
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases found intracellularly and are nonlysosomal cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific forms. The ubiquitous enzymes are heterodimers with distinct large catalytic subunits and a common small regulatory subunit.
This gene encodes the large subunit of the ubiquitous enzyme Calpain 1. Multiple transcript variants encoding two isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76 (Autosomal Recessive) and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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