Thermo Fisher Scientific Phospho-DOK2 (Tyr345) Polyclonal Antibody
인간 및 생쥐 시료에서 Tyr345 인산화된 DOK2 단백질을 검출하는 폴리클로날 항체. Western blot 및 IHC(파라핀) 실험에 적합. 고순도 정제 및 안정적 액상 형태로 제공되며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DOK2 (Accession O60496), corresponding to amino acid residues around phosphorylated Tyr345 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903227 |
Product Specific Information
Antibody detects endogenous levels of DOK2 only when phosphorylated at Tyr345.
Target Information
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase.
It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML.
This encoded protein binds p120 from CML cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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