Thermo Fisher Scientific Pancreatic duodenal homeobox-1 protein (PDX1) Monoclonal Antibody (PCRP-PDX1-2C11)
인간 PDX1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체입니다. ICC/IF, Flow Cytometry, Peptide Array에 사용 가능하며, 비결합형 액상 형태로 제공됩니다. 단백질 A/G로 정제되었으며 PBS(pH 7.4) 저장 버퍼를 사용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-PDX1-2C11 |
| Immunogen | Recombinant full-length human PDX1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression.
Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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