Thermo Fisher Scientific GABARAP Polyclonal Antibody
GABARAP 단백질 검출용 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 ICC/IF에 적합하며, 높은 특이성과 재현성을 제공. 인간 반응성, 다양한 종에서 예측 반응성 확인. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:10,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GABARAP (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735798 |
Product Specific Information
- Positive Control: 293T, Jurkat, Raji, NCI-H929, A431, HeLa, human GABARAP-transfected 293T
- Predicted Reactivity: Mouse (100%), Rat (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl⁻ conductance that inhibits neuronal firing in the central nervous system.
It activates both ionotropic (GABAA) and metabotropic (GABAB) receptors, as well as a third class called GABAC.
GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport and receptor-cytoskeleton interactions.
GABARAP belongs to the MAP1 or ATG8-like family, and recent studies show that MAPK15/ERK8 interacts with ATG8 family proteins to regulate autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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