Thermo Fisher Scientific GABARAP Polyclonal Antibody
인간 GABARAP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot과 Immunocytochemistry에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며 장기 보관 시 -20°C에서 안정적입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GABARAP (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.48 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.0, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2735799 |
Product Specific Information
- Positive Control: 293T, U87-MG, SK-N-SH, IMR32, SK-N-AS
- Predicted Reactivity: Mouse (100%), Rat (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter that increases Cl⁻ conductance, inhibiting neuronal firing in the central nervous system. It activates ionotropic (GABAA) and metabotropic (GABAB) receptors, as well as GABAC receptors.
GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport and receptor-cytoskeleton interaction.
GABARAP belongs to the MAP1 or ATG8-like family, and studies show that MAPK15/ERK8 interacts with ATG8 family proteins to regulate autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일 정보: PA5-78366_GABARAP_O95166-1_Rabbit.svg, PA5-78366_GABARAP_O95166-1_Rabbit_PDP.jpeg)
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