Thermo Fisher Scientific MCM2 Monoclonal Antibody (UMAB238), UltraMAB
MCM2 단백질을 표적으로 하는 Thermo Fisher Scientific의 UMAB238 단클론 항체. 인간 시료에 반응하며 Western blot 및 IHC에 적합. PBS 기반 안정화 버퍼로 보존, 동결건조 형태. DNA 복제 조절 관련 연구용으로 최적화된 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB238 |
| Immunogen | Full-length human recombinant MCM2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of ~1 mg/mL.
- For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. It is a human nuclear protein crucial for the cell cycle, participating in the onset of DNA replication and cell division. MCM2 is similar to early S-phase proteins and mapped to chromosome 3q21. CDCL1, a related gene, is considered a candidate oncogene associated with chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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