Thermo Fisher Scientific AK1 Polyclonal Antibody, MaxPab
AK1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 및 생쥐 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 보존되어 있으며 방부제는 포함되지 않습니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | AK1 (NP_000467.1, 1 a.a.–194 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MEEKLKKTKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRSEVSSG SARGKKLSEI MEKGQLVPLE TVLDMLRDAM VAKVNTSKGF LIDGYPREVQ QGEEFERRIG QPTLLLYVDA GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD SVFSQVCTHL DALK
Target Information
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides.
Three isozymes of adenylate kinase have been identified in vertebrates: AK1, AK2, and AK3.
- AK1 is found in the cytosol of skeletal muscle, brain, and erythrocytes.
- AK2 and AK3 are located in mitochondria of tissues such as liver and heart.
AK1 was identified due to its association with a rare genetic disorder causing nonspherocytic hemolytic anemia, in which a mutation in the AK1 gene reduces the catalytic activity of the enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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