Thermo Fisher Scientific AK1 Monoclonal Antibody (3G8-1B11)
AK1 단백질을 인식하는 Thermo Fisher Scientific의 3G8-1B11 단클론 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간 시료 반응성이 있으며, PBS 버퍼에 보존된 비결합형 액상 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G8-1B11 |
| Immunogen | AK1 (AAH01116, 1–194 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MEEKLKKTNI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRSEVSSG SARGKKLSEI MEKGQLVPLE TVLDMLRDAM VAKVNTSKGF LIDGYPREVQ QGEEFERRIG QPTLLLYVDA GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD SVFSQVCTHL DALK
Target Information
Adenylate kinase is an enzyme that regulates the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides.
Three isozymes of adenylate kinase have been identified in vertebrates: AK1, AK2, and AK3.
- AK1: Found in the cytosol of skeletal muscle, brain, and erythrocytes
- AK2 & AK3: Found in the mitochondria of tissues such as liver and heart
AK1 is associated with a rare genetic disorder causing nonspherocytic hemolytic anemia, where a mutation in the AK1 gene reduces the enzyme’s catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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