Thermo Fisher Scientific AK1 Monoclonal Antibody (4C2-1A8)
Thermo Fisher Scientific의 AK1 단클론 항체(4C2-1A8)는 인간 Adenylate Kinase 1을 인식하는 Mouse IgG1 항체로, WB 및 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, 보존제 무첨가, 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C2-1A8 |
| Immunogen | AK1 (AAH01116, 1–194 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MEEKLKKTNI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRSEVSSG SARGKKLSEI MEKGQLVPLE TVLDMLRDAM VAKVNTSKGF LIDGYPREVQ QGEEFERRIG QPTLLLYVDA GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD SVFSQVCTHL DALK
Target Information
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides.
Three isozymes of adenylate kinase have been identified in vertebrates: AK1, AK2, and AK3.
- AK1: Found in the cytosol of skeletal muscle, brain, and erythrocytes
- AK2 / AK3: Found in mitochondria of tissues including liver and heart
AK1 was identified due to its association with a rare genetic disorder causing nonspherocytic hemolytic anemia, where a mutation in the AK1 gene reduces the catalytic activity of the enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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