Thermo Fisher Scientific AK1 Monoclonal Antibody (3A6-1F5)
AK1 단백질을 인식하는 Thermo Fisher Scientific의 마우스 모노클로날 항체. Western blot, ICC/IF, ELISA, IP에 사용 가능. 인간 유래 단백질에 반응하며, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A6-1F5 |
| Immunogen | AK1 (AAH01116, 1–194 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MEEKLKKTNI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRSEVSSG SARGKKLSEI
MEKGQLVPLE TVLDMLRDAM VAKVNTSKGF LIDGYPREVQ QGEEFERRIG QPTLLLYVDA
GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD
SVFSQVCTHL DALKTarget Information
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides.
Three isozymes of adenylate kinase have been identified in vertebrates: AK1, AK2, and AK3.
- AK1 is found in the cytosol of skeletal muscle, brain, and erythrocytes.
- AK2 and AK3 are located in the mitochondria of tissues such as liver and heart.
AK1 has been associated with a rare genetic disorder causing nonspherocytic hemolytic anemia, where mutations in the AK1 gene reduce the enzyme’s catalytic activity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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