Thermo Fisher Scientific MRP3 (Multidrug Resistance-Associated Protein 3) Monoclonal Antibody (ABCC3, 2971)
MRP3(ABCC3)에 특이적인 mouse monoclonal antibody. IHC(P) 및 peptide array에 사용 가능. Recombinant fragment(aa 815-957)을 면역원으로 제작. Protein A/G 정제, PBS buffer에 보존. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ABCC3, 2971 |
| Immunogen | Recombinant fragment (around aa 815–957) of human MRP3 (ABCC3) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein belongs to the MRP subfamily, which is involved in multidrug resistance. Although the specific function of this protein has not yet been determined, it may play a role in the biliary and intestinal excretion of organic anions.
Alternatively spliced variants encoding different isoforms have been described, though not all have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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