Thermo Fisher Scientific CD19 Monoclonal Antibody (LT19), PerCP
인간 CD19 항원을 인식하는 마우스 단클론 항체로, PerCP로 표지되어 유세포분석(Flow Cytometry)에 적합합니다. B세포 표면 마커 분석에 활용되며, 4°C 암소 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 10 µL/1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LT19 |
| Immunogen | Daudi human Burkitt lymphoma cell line |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11156377 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells. Expression is lost on plasma cells.
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and plays a central role in B cell receptor signaling and regulation. CD19 acts as a signal-amplifying coreceptor, lowering the threshold for antigen receptor-dependent stimulation. Mutations can lead to hypogammaglobulinemia, whereas overexpression may cause B cell hyperactivity. CD19 expression is also observed in B cell precursor leukemias and certain myeloid leukemia cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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