Thermo Fisher Scientific EVC2 Polyclonal Antibody
EVC2 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF, ELISA 등에 사용 가능. Human 시료에 반응하며, Protein A로 정제된 액상 형태. 뼈 형성과 골격 발달 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human EVC2 (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01 M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The EVC2 gene encodes a protein involved in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene arranged in a head-to-head configuration, cause Ellis-van Creveld syndrome (chondroectodermal dysplasia), an autosomal recessive skeletal dysplasia. Mutations can also lead to acrofacial dysostosis Weyers type (Curry-Hall syndrome), characterized by limb and facial abnormalities. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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