Thermo Fisher Scientific IFN gamma Monoclonal Antibody (XMG1.2), Alexa Fluor 700, eBioscience
마우스 IFN-γ를 인식하는 중화용 랫 IgG1 단클론 항체로, Alexa Fluor 700 형광 표지. Flow cytometry 및 intracellular staining에 최적화. 633 nm 레이저로 여기, 723 nm 방출. PBS buffer, 4°C 보관, 동결 금지.
- 카탈로그번호
- 56-7311-8x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IFN gamma Monoclonal Antibody (XMG1.2), Alexa Fluor 700, eBioscience
Thermo Fisher Scientific IFN gamma Monoclonal Antibody (XMG1.2), Alexa Fluor 700, eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (IHC) | - | View 3 publications |
| Flow Cytometry (Flow) | 0.06 µg/test | View 94 publications |
| ELISA | - | View 3 publications |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rat / IgG1, kappa |
| Recommended Isotype Control | Rat IgG1 kappa Isotype Control (eBRG1), Alexa Fluor™ 700 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | XMG1.2 |
| Conjugate | Alexa Fluor™ 700 |
| Excitation / Emission Max | 696 / 719 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2688062 |
Available Formats
- Unconjugated
- Alexa Fluor 488
- Alexa Fluor 561
- Alexa Fluor 660
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395 / 615 / 661 / 737 / 805
- Brilliant Violet 421 / 480 / 605 / 650 / 711 / 786
- eFluor 450 / 660
- FITC
- Functional Grade
- PE / PE-Cyanine7 / PE-eFluor 610
- PerCP-Cyanine5.5
- Request custom conjugation available
Product Specific Information
The XMG1.2 antibody reacts with mouse interferon (IFN) gamma and functions as a neutralizing antibody. Mouse IFN gamma is a 20 kDa factor produced by activated T, B, and NK cells, exhibiting antiviral and antiparasitic activity. It synergizes with cytokines such as TNF alpha to inhibit proliferation of normal and transformed cells.
This antibody is suitable for intracellular staining followed by flow cytometric analysis. Tested by intracellular staining and flow cytometric analysis of stimulated mouse splenocytes. Recommended usage ≤0.6 µg per test (100 µL final volume).
Alexa Fluor™ 700 emits at 723 nm and is excited with a red laser (633 nm). Ensure instrument compatibility (typically requires 685 LP mirror and 710/20 filter).
Excitation: 633–647 nm
Emission: 723 nm
Laser: Red Laser
Target Information
IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation and immune interferon produced mainly by T lymphocytes and NK cells. It is a dimeric glycoprotein (~45 kDa) consisting of two 146 amino acid subunits. IFN gamma displays species-specific biological activity; human IFN gamma does not cross-react with mouse.
Functions include antiviral and antiproliferative activity, induction of MHC class I/II, macrophage activation, and enhanced immunoglobulin secretion. It acts through IFN gamma receptor I and II via the JAK-STAT pathway. Expression is upregulated by IL2, FGF basic, EGF, and downregulated by vitamin D3 or DMN.
Mutations in IFN gamma gene are associated with aplastic anemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.