Thermo Fisher Scientific Insulin Monoclonal Antibody (2D11.H5)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Store vial at -20°C prior to opening.
• Aliquot and freeze at -20°C or below for extended storage.
• Avoid repeated freeze/thaw cycles.
• Centrifuge if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.

Reactivity:
Reacts specifically with insulin from human and swine sources.
No cross-reactivity with insulin from mouse or rat.
Cross-reactivity with insulin from other sources not determined.

Target Information

Insulin is a peptide hormone secreted by pancreatic β-cells that regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, triglyceride formation, and protein/nucleic acid synthesis.
Insulin is a 51-amino acid polypeptide derived from proinsulin, which is cleaved into A and B chains linked by disulfide bonds and one molecule of C-peptide.
Insulin deficiency leads to diabetes mellitus, a major cause of morbidity and mortality. Insulin is also found in β-cell tumors such as insulinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.