
Thermo Fisher Scientific TECK Polyclonal Antibody
TECK 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 순도(>95%) 보유. 인간 시료 반응성. 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CCL25: 21–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719776 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Chemokines are important in regulating the trafficking of developing T cells within the thymus. Chemokine C-C thymus expressed chemokine (TECK), also known as chemokine ligand 25 (CCL25), small inducible cytokine A25, or CK b-15, is expressed mainly in thymic dendritic and epithelial cells, as well as in the small intestine.
TECK, a CCR9 ligand, suppresses immature myeloid progenitor subsets stimulated by multiple growth factors. It delivers signals through CCR9, crucial for thymocyte navigation. Bone marrow pre-pro-B cells and IL-7/Flt-3 ligand–responsive progenitors migrate toward TECK, a response lost in later B cell development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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