Thermo Fisher Scientific IGF2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 IGF2 폴리클로날 항체로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 보장. PBS/glycerol buffer에 보관되며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human IGF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719773 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
The insulin-like growth factors (IGFs) are mitogenic, polypeptide growth factors that promote proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are mainly produced by the liver, though many tissues produce IGFs at specific developmental stages. Belonging to the insulin gene family, IGFs share structural and functional similarities with insulin but exhibit stronger growth-promoting activity. IGF-II expression is influenced by placental lactogen, while IGF-I is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), with IGF-II also signaling through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins containing N- and C-terminal propeptides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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