Thermo Fisher Scientific AGR2 Polyclonal Antibody
AGR2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC(P)에서 1:100~1:300 희석으로 사용 가능. Human 및 Mouse 반응성, 항원 친화 크로마토그래피로 정제. PBS+30% glycerol 보존, 4°C 단기 또는 -20°C 장기 보관.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:300
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to an internal portion of the human protein (within residues 50–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 30% glycerol |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11157470 |
Product Specific Information
This antibody is predicted to react with bovine based on 100% sequence homology.
It is not recommended for ICC/IF applications.
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family.
They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition.
They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumors.
AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas, and endometrial carcinomas.
AGR2 expression is positively correlated with the estrogen receptor (ER) and negatively correlated with the epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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