Thermo Fisher Scientific FASTK Polyclonal Antibody
FASTK 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 인간 FASTK 단백질 연구용으로 적합하며, 세포사멸 관련 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FASTK. Recombinant protein control fragment (Product # RP-96530) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641511 |
Product Specific Information
Immunogen sequence:
GQAASSATTR DPAQRVVLVL RERWHFCRDG RVLLGSRALR ERHLGLMGYQ LLPLPFEELE SQRGLPQLKS YLRQKLQAL
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 33%
Target Information
The protein encoded by this gene is a member of the serine/threonine protein kinase family.
This kinase is activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein.
The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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