Thermo Fisher Scientific CYBA Monoclonal Antibody (44.1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

44.1

Immunogen

Partially Purified human neutrophil flavocytochrome b if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CYBA,uniProtId:P13498-1,ncbiNodeId:9606,antigenRange:1-195,antigenLength:195,antigenImageFileName:MA5-18049_CYBA_P13498-1_House_mouse.svg,antigenImageFileNamePDP:MA5-18049_CYBA_P13498-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2539432

Product Specific Information

This antibody is specific for human Cytochrome b245 light chain aa 29-33 (TAGRF) and 183-188 (PQVNPI). The immunogen was prepared using partially purified human neutrophil flavocytochrome b (heparin Ultrogel/lectin affinity purification in Triton X-100).

This target has a predicted molecular weight of 21 kDa.

Target Information

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.