
Thermo Fisher Scientific Malondialdehyde Monoclonal Antibody (11E3), PerCP
Malondialdehyde 단백질 결합체를 특이적으로 인식하는 PerCP 결합 단일클론 항체입니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. 다른 알데하이드 변형 단백질과 교차 반응하지 않으며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Malondialdehyde Monoclonal Antibody (11E3), PerCP
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| ELISA | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 11E3 |
| Immunogen | Synthetic Malondialdehyde modified Keyhole Limpet Hemocyanin (KLH) |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932261 |
Available Formats
- Unconjugated (MA5-27560)
- APC (MA5-45805)
- FITC (MA5-45806)
- PE (MA5-45808)
- Custom conjugation available upon request
Product Specific Information
A 1:1,000 dilution of MA5-45807 was sufficient for detection of Malondialdehyde in 2 µg of Malondialdehyde conjugated to BSA by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.
Specific for Malondialdehyde conjugated proteins. Does not detect free Malondialdehyde.
No cross-reactivity with Acrolein, Crotonaldehyde, Hexanoyl Lysine, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, or Methylglyoxal modified proteins.
Target Information
Malondialdehyde (CH₂(CHO)₂) is an organic compound and a byproduct of lipid metabolism. It is a reactive electrophile species that causes cellular stress and forms covalent protein adducts known as advanced lipoxidation end products (ALE).
Malondialdehyde also forms mutagenic DNA adducts when reacting with deoxyadenosine and deoxyguanosine in DNA. It is found in many foods, especially in rancid ones.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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