Thermo Fisher Scientific Phospho-Nuclear receptor ROR gamma (Ser203) Polyclonal Antibody
Mouse ROR gamma 인산화(Ser203)에 특이적인 Rabbit Polyclonal Antibody로, WB와 ELISA에 사용 가능. Affinity chromatography로 정제된 액상 형태이며, -20°C에서 보관. 연구용으로 세포 내 RORγ 신호 조절 및 T helper 세포 분화 연구에 적합.
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Thermo Fisher Scientific Phospho-Nuclear receptor ROR gamma (Ser203) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| ELISA | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified Anti-receptor ROR gamma pS203 antibody prepared from rabbit serum immunized with synthetic peptide phosphorylated at serine 203 of mouse receptor ROR gamma protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid freeze/thaw cycles. Centrifuge product if not completely clear after standing at room temperature.
Stable for several weeks at 4°C as undiluted liquid. Dilute only prior to immediate use.
Anti-nuclear receptor ROR gamma pS203 is directed against mouse receptor ROR gamma phosphorylated at the serine 203 position. BLAST analysis suggests reactivity with Pongo abelii based on 100% homology for the immunogen sequence.
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor of the ROR/RZR orphan nuclear receptor subfamily. It functions as a ligand-activated transcription factor and is essential for lymphoid organogenesis (lymph nodes and Peyer’s patches).
It regulates apoptosis during thymopoiesis, inhibits Fas ligand and IL2 expression, and directs differentiation of proinflammatory IL-17+ T helper cells.
ROR gamma shares 50–51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. Highly expressed in skeletal muscle and found at lower levels in other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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